Weight loss and survival in lethal H5N1 virus challenged mice. Mice were challenged with 10LD50 of H5N1 virus, clade1: VN/1194 or clade2.3.4: SZ/406H, and monitored daily for 2 weeks post-challenge. A. Percentage change (%) of mouse body weight. Each point represents mean body weight of 10 mice per group. B. Survival rate. The significant differences (P < 0.0001) of M2e-MAP+FCA/FIA versus FCA/FIA and M2e-MAP+alum versus alum are indicated as * and **, respectively.