Figure 4From: An M2e-based multiple antigenic peptide vaccine protects mice from lethal challenge with divergent H5N1 influenza virusesWeight loss and survival in lethal H5N1 virus challenged mice. Mice were challenged with 10LD50 of H5N1 virus, clade1: VN/1194 or clade2.3.4: SZ/406H, and monitored daily for 2 weeks post-challenge. A. Percentage change (%) of mouse body weight. Each point represents mean body weight of 10 mice per group. B. Survival rate. The significant differences (P < 0.0001) of M2e-MAP+FCA/FIA versus FCA/FIA and M2e-MAP+alum versus alum are indicated as * and **, respectively.Back to article page