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Figure 8 | Virology Journal

Figure 8

From: Variability in a dominant block to SIV early reverse transcription in rhesus monkey cells predicts in vivo viral replication and time to death

Figure 8

B-LCL susceptibility to VSV-G pseudotyped SIV-GFP correlates with in vivo plasma viremia and time to death following rhesus monkey challenge with SIVmac251 or SHIV-89.6P. Positive correlation between % GFP+ B-LCL following VSV-G pseudotyped SIVsmE543-GFP in vitro infection of rhesus monkey B-LCL and (A) in vivo peak plasma viremia of monkeys (day 14 post-infection) as measured by RT assay, and (B) time to death following in vivo infection with SHIV-89.6P. Positive correlation between % GFP+ B-LCL following VSV-G pseudotyped SIVmac239-GFP in vitro infection of rhesus monkey B-LCL and (C) in vivo peak plasma virus RNA levels of monkeys (day 14 post-infection) and positive trend with (D) time to death following in vivo infection with SIVmac251.

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Virology Journal

ISSN: 1743-422X