Figure 3From: Variability in a dominant block to SIV early reverse transcription in rhesus monkey cells predicts in vivo viral replication and time to deathPositive correlation between rhesus monkey PBMC susceptibility to infection with wild type SIVsmE660 and a single cycle VSV-G pseudotyped SIVsmE660-GFP construct. (A) PBMC susceptibility to SIVsmE660 replication was defined by TCID50, and SIVsmE543-GFP infection was defined as % GFP+ PBMC following infection with VSV-G pseudotyped SIVsmE660-GFP determined using flow cytometric analysis. (B) Positive correlation between rhesus monkey PBMC susceptibility to SIVsmE660 infection, as defined by TCID50, and area under the curve (AUC) of % GFP+ B-LCL following infection with serial dilutions of VSV-G pseudotyped SIVsmE543-GFP. (C) Positive correlation between rhesus monkey PBMC susceptibility to SIVmac239 infection, as defined by TCID50, and area under the curve (AUC) of % GFP+ B-LCL following infection with serial dilutions of VSV-G pseudotyped SIVmac239-GFP.Back to article page