Figure 1From: Efficient inhibition of hepatitis B virus replication by hepatitis delta virus ribozymes delivered by targeting retrovirusInhibition of HBsAg and HBeAg secretion in HepG2215 cell supernatants by HDV ribozyme with or without pHSA. A: HepG2215 cells were transduced with a retrovirus carrying the HDV ribozyme with and without pHSA. At 48 hours after infection, the supernatants were collected, and ELISA was performed to detect HBsAg. The level of HBsAg was significantly decreased with pHSA (P < 0.001). The values are the mean ± S.D. values of 3 independent tests; B: ELISA detecton of HBeAg. Rz could significantly inhibit HBeAg expression with pHSA (P = 0.001).Back to article page