Table 1 Comparison of viral proteins ORF 3 and M of hCoV-NL63 and SARS-CoVa
Viral protein | hCoV-NL63 ORF 3 | SARS-CoV ORF 3a | hCoV-NL63 M | SARS-CoV M |
|---|---|---|---|---|
No. amino acids [size in kDa] | 225 [26] | 274 [31] | 226 [26] | 221 [25] |
No. transmembrane domains (position) | 3 (39-61, 70-92, 97-116) | 3 (34-56, 77-99,103-125) | 4 (20-38, 43-65, 75-97, 129-151) | 3 (15-37, 50-72, 77-99) |
No. cysteine residues (position) | 4 (72, 131, 137, 182) | 8 (81, 117, 121, 127, 130, 133, 148, 157) | 4 (54, 67, 90, 180) | 3 (158, 63, 85) |
No. putative N-glycosylation sites (position) | 3 (16, 119, 126) | 1 (227b) | 3 (3, 19, 188) | 1 (4c) |
No. putative O-glycosylation sites (position) | - | 3 (28c, 32c, 267-271) | - | - |