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Table 4 Comparison of the effectiveness of oseltamivir and zanamivir against the oseltamivir-susceptible and oseltamivir-resistant influenza A(H1N1) infections

From: A two-year survey of the oseltamivir-resistant influenza A(H1N1) virus in Yamagata, Japan and the clinical effectiveness of oseltamivir and zanamivir

  Oseltamivir-treated cases   Zanamivir-treated cases  
  2007-2008 Oseltamivir-susceptible
(n = 8)
2008-2009 Oseltamivir-resistant
(n = 25)
P-value 2007-2008 Oseltamivir-susceptible
(n = 4)
2008-2009 Oseltamivir-resistant
(n = 6)
P-value
Age, years; median (range) 6 (1-9) 5 (2-9) .8155 8 (7-11) 11 (9-12) .0506
Maximum body temperature, °C; median (range) 39.3 (38.9-39.8) 39.1 (38.2-40.6) .3874 39.2 (38.6-39.6) 39.0 (38.2-39.6) .5906
Total febrile period, days; median (range) 3.5 (2-5) 4 (2-7) .0503 3 (2-4) 3 (3-4) .4642
Duration of fever after the start of therapy, days; median (range) 1.5 (1-2) 2 (1-6) .0356 1 (1-2) 1 (1-3) .6926