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Table 4 Comparison of the effectiveness of oseltamivir and zanamivir against the oseltamivir-susceptible and oseltamivir-resistant influenza A(H1N1) infections

From: A two-year survey of the oseltamivir-resistant influenza A(H1N1) virus in Yamagata, Japan and the clinical effectiveness of oseltamivir and zanamivir

 

Oseltamivir-treated cases

 

Zanamivir-treated cases

 
 

2007-2008 Oseltamivir-susceptible

(n = 8)

2008-2009 Oseltamivir-resistant

(n = 25)

P-value

2007-2008 Oseltamivir-susceptible

(n = 4)

2008-2009 Oseltamivir-resistant

(n = 6)

P-value

Age, years; median (range)

6 (1-9)

5 (2-9)

.8155

8 (7-11)

11 (9-12)

.0506

Maximum body temperature, °C; median (range)

39.3 (38.9-39.8)

39.1 (38.2-40.6)

.3874

39.2 (38.6-39.6)

39.0 (38.2-39.6)

.5906

Total febrile period, days; median (range)

3.5 (2-5)

4 (2-7)

.0503

3 (2-4)

3 (3-4)

.4642

Duration of fever after the start of therapy, days; median (range)

1.5 (1-2)

2 (1-6)

.0356

1 (1-2)

1 (1-3)

.6926