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Table 1 Evaluation the immunohistochemical staining results of patients' sera to adult human cerebra

From: The cross-reactivity of the enterovirus 71 to human brain tissue and identification of the cross-reactivity related fragments

Sera no/human sex/age

Clinical features/Diagnosis

Day of sera collection after onset

Evaluation score

NORMAL-1/F/1.5

NO

-

-

NORMAL-2/M/3.5

NO

-

-

NORMAL-3/F//4

NO

-

-

NORMAL-4/M/2.6

NO

-

-

NORMAL-5/F/23

NO

-

-

CNILASTB-1/M/1.5

Fever, HMFD/Brain stem encephalitis

1

+ + +

CNILASTB-2/F/2.8

Fever, irritability, myoclonus, HFMS/Brain stem encephalitis

1

+ +

CNILASTB-3/M/3.6

Fever, myoclonus, HMFD/Brain stem encephalitis

1

+ + +

CNILASTB-4/F/4.5

Fever, irritability, HMFD/Brain stem encephalitis

3

+ + + +

CNILASTB-5/M/2.5

HMFD/-

0

+ +

CNILASTB-6/M/1.8

HMFD/-

0

+ +

CNILASTB-7/M/1.5

Fever, vomiting, irritability, HMFD/Brain stem encephalitis

0

+ + +

CNILASTB-8/F/2.4

HMFD/-

0

+ +

CNILASTB-9/F/2.5

Fever, vomiting, motor weakness/Aseptic meningitis

3

+ + + +

CNILASTB-10/M/1.5

Fever, vomiting, HMFD/Brain stem encephalitis

1

+ + +

CNILASTB-11/M/2.2

Fever, irritability, myoclonus, HMFD/Brain stem encephalitis

2

+ + +

CNILASTB-12/M/1.6

HMFD/-

0

+

CNILASTB-13/M/1.2

HMFD/-

0

+ +

CNILASTB-14/M/1.8

Fever, irritability,/Brain stem encephalitis

0

+ +

CNILASTB-15/F/2.6

Fever, lethargy, ataxia, HFMS/Brain stem

encephalitis, neurogenic shock, pulmonary edema

0

+ + + +

CNILASTB-16/M/4.6

HFMD/-

0

+

CNILASTB-17/M/5.4

HFMD/-

1

+ +

CNILASTB-18/F/3.2

Fever, vomiting, lethargy, motor weakness/Aseptic meningitis

1

+ + +

CNILASTB-19/F/5.2

HFMD/-

2

+

CNILASTB-20/F/5

Fever, vomiting, lethargy, nystagmus, shock/Brain stem encephalitis, pulmonary edema

1

+ + +

CNILASTB-21/M/3.6

Fever, vomiting, headache/Aseptic meningitis

2

+ + + +

CNILASTB-22/F/3.2

HFMD/-

0

+

CNILASTB-23/F/2.4

Irritability, lethargy, apathy, myoclonus, HFMS/Aseptic meningitis

2

+ + +

CNILASTB-24/M/1.7

Fever, vomiting, lethargy, nystagmus, myoclonus, shock/Brain stem encephalitis, neurogenic shock, pulmonary edema

2

+ + +

CNILASTB-25/M/3.4

HFMD/-

1

+ +

CNILASTB-26/F/4.6

HFMD/-

1

+ +

CNILASTB-27/F/2.8

Fever, vomiting, headache, irritability, HMFD/Aseptic meningitis

1

+ +

CNILASTB-28/M/3

Fever, lethargy, myoclonus, shock/Aseptic meningitis

2

+ + +

CNILASTB-29/F/2

HFMD/-

2

+ +

CNILASTB-30/M/3.2

Fever, vomiting, headache, myoclonus, HFMS/Brain stem

encephalitis

1

+ + + +

  1. - No obvious staining was observed;
  2. + 0~10% cell was stained;
  3. + + 11%~20% cell was stained;
  4. + + + 21%~30% cell was stained;
  5. + + + + 31%~40% cell was stained.
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Virology Journal

ISSN: 1743-422X