Table 2 Effects of formaldehyde and glutaraldehyde on infectivity of HCVcc in human serum
From: Thermal stability and inactivation of hepatitis C virus grown in cell culture
Treatment | Infectious titer (FFU/ml) | IFA result | |
|---|---|---|---|
2nd cell passage | 3rd cell passage | ||
Formaldehyde (0.037%) | |||
0 h | (8.5 ± 0.7) × 104a | NTb | NT |
1.0 h | (1.9 ± 0.4) × 104 | NT | NT |
2.0 h | (3.5 ± 0.7) × 103 | NT | NT |
3.0 h | (1.0 ± 0.0) × 103 | NT | NT |
4.0 h | < 1.0 × 103 | negative | negative |
Glutaraldehyde (0.01%) | |||
0 min | (9.5 ± 0.7) × 104a | NT | NT |
10 min | (1.8 ± 0.2) × 104 | NT | NT |
20 min | (2.5 ± 0.7) × 103 | NT | NT |
30 min | < 1.0 × 103 | Positive | NT |
40 min | < 1.0 × 103 | negative | negative |