Skip to main content

Table 4 Amino acid composition of non-polar, neutral and polar basic and acidic amino acids in rapid responders (15 variants) and in breakthrough responders (BT)

From: Mutations in the E2-PePHD region of hepatitis C virus genotype-3a and correlation with response to interferon and ribavirin combination therapy in Pakistani patients

PePHD

Polar a.a composition

Non polar a.a composition

 

+ve charged (basic)

- ve charged (acidic)

Neutral

 

RR group (15 variants)

Lys(K) 0.00

Asp(D) 0.00

Ser(S) 16.67

Ala(A) 0.56

 

His(H) 13.33

Glu(E) 8.33

Thr(T) 16.11

Val(V) 0.00

 

Arg(R) 8.89

 

Gln(Q) 11.11

Leu(L) 16.67

   

Cys(C) 0.00

Ile(I) 0.00

   

Asn(N) 0.00

Gly(G) 0.00

   

Tyr(Y) 0.00

Trp(W) 0.00

    

Phe(F) 0.00

    

Pro(P) 8.33

    

Met(M) 0.00

Average composition

22.22

8.33

43.89

25.56

BT group

Lys(K) 0.00

Asp(D) 0.00

Ser(S) 16.67

Ala(A) 0.00

 

His(H) 16.67

Glu(E) 8.33

Thr(T) 16.67

Val(V) 0.00

 

Arg(R) 8.33

 

Gln(Q) 2.98

Leu(L) 22.02

   

Cys(C) 0.00

Ile(I) 0.00

   

Asn(N) 0.00

Gly(G) 0.00

   

Tyr(Y) 0.00

Trp(W) 0.00

    

Phe(F) 0.00

    

Pro(P) 8.33

    

Met(M) 0.00

Average composition

25.00

8.33

36.32

30.35