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Figure 3 | Virology Journal

Figure 3

From: Initiation of bacteriophage T4 DNA replication and replication fork dynamics: a review in the Virology Journal series on bacteriophage T4 and its relatives

Figure 3

Double-strand break repair models . The SDSA model for DSB repair invokes a limited amount of bubble-migration synthesis using one end of a double-strand break, followed by extrusion of the extended 3' end and capture of the second broken end (panel A). The extensive chromosomal replication (ECR) model invokes two successive rounds of semi-conservative replication (panel B). Depending on which product of the first round of replication is chosen for the second round of strand invasion, the two broken ends of the original double-strand break can end up in different molecules rather than being linked back together again. The final stages of elongation are not shown, but would result in three complete product molecules.

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Virology Journal

ISSN: 1743-422X