Figure 6

Comparison of gp10 with other baseplate proteins; reprinted from [11]. A, Stereo view of the superposition of gp10, gp11, and gp12. For clarity, the finger domain of gp11 and the insertion loop between β-strands 2 and 3 of gp12 are not shown. The β-strands are numbered 1 through 6 and the α-helix is indicated by "A". B, The structure-based sequence alignment of the common flower motifs of gp10, gp11, and gp12. The secondary structure elements are indicated above the sequences. The insertions between the common secondary structure elements are indicated with the number of inserted residues. The residues and their similarity are highlighted using the color scheme of the CLUSTAL program [89]. The alignment similarity profile, calculated by CLUSTAL, is shown below the sequences. C, The topology diagrams of the flower motif in gp10, gp11, and gp12. The circular arrows indicate interacting components within each trimer. The monomers are colored red, green, and blue. The numbers indicate the size of the insertions not represented in the diagram.