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Figure 3 | Virology Journal

Figure 3

From: Conserved epitopes of influenza A virus inducing protective immunity and their prospects for universal vaccine development

Figure 3

Indirect anti-influenza mechanisms of protection via Fc region of antibodies. Infected cells are killed via antibody-dependent cell-mediated cytotoxicity (ADCC) after activation of natural killer cells (NK cell) by Fc region of IgG (red arrow). Phagocytosis of viral particles or infected cells (not shown) is mediated through recognition of Fc region of IgG by macrophages (green arrows) or by interaction of complement with complement receptor on macrophages (CR) (blue arrow).

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