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Figure 3 | Virology Journal

Figure 3

From: The Meq oncoprotein of Marek's disease virus interacts with p53 and inhibits its transcriptional and apoptotic activities

Figure 3

Meq inhibits p53-mediated apoptosis. Flag-p53 was co-transfected into CEFs with Flag-Meq or Flag-Meq-Δp53BD at a 1:10 molar ratio. (A) Apoptotic cells (red) were stained with a TUNEL assay kit. The cells were also stained for DNA with DAPI (blue). (B) The percentage of apoptotic cells (red) was determined and is shown on the graph as the average ± standard error from three experiments. More than 500 cells were examined for each experiment. *p < 0.05 compared with cells transfected with Flag-p53 alone (Flag-p53+Flag-Vec).

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Virology Journal

ISSN: 1743-422X