Table 6 Comparison of antigenic sites in amino acid sequences of neuraminidase proteins (H9N2).
1997 | 1998 | 1999 | 2003 | 2008 | 2009 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
A/Hong Kong/1074/97 | A/Shantou/239/98 | A/Shaoguan/408/98 | A/Shaoguan/447/98 | A/Hong Kong/1073/99 A/Hong Kong/1074/99 | A/Guangzhou/333/99 | A/Hong Kong/2108/03 | A/Hong Kong/3239/08 | A/Hong Kong/33982/2009 A/Hong Kong/35820/2009 | |||||||||
Position | Sequence | Position | Sequence | Position | Sequence | Position | Sequence | Position | Sequence | Position | Sequence | Position | Sequence | Position | Sequence | Position | Sequence |
98 | FSKDNSIRL | 83 | FSKDNSIRL | 97 | FSKDNSIRL | 78 | FSKDNSIRL | 98 | FSKDNSIRL | 100 | FSKDNSIRL | 100 | FSKDNSIRL | 92 | FSKDNSIRL | 92 | FSKDNSIRL |
295 | GSNRPVLYI | 280 | GSNRPVLYI | 294 | GSNRPVLYI | 275 | GSNRPVLYI | 295 | GSNRPVLYI | 248 | GRADTRILF | 297 | GSNRPVLYI | 289 | GSNRPVLYI | 19 | ALFATTMTL |
459 | GANINFMSI | 231 | GRADTRILF | 152 | HRTLLMNEL | 133 | HRTLLMNEL | 459 | GANINFMSI | 155 | HRTLLMNEL | 248 | GRADTRILF | 102 | ASGDIWVTR | 240 | GRADTRILF |
153 | HRTLLMNEL | 138 | HRTLLMNEL | 145 | TTHDRIPHR | 126 | TTHDRIPHR | 153 | HRTLLMNEL | 378 | RVIGGWITA | 155 | HRTLLMNEL | 147 | HRTLLMNEL | 289 | GSNRPVLFI |
277 | SCYPRYPEV | 282 | NRPVLYINM | 296 | NRPVLYINM | 277 | NRPVLYINM | 277 | SCYPRYPEV | 279 | SCYPRYPEV | 458 | WPDGANINL | 291 | NRPVLYINM | 102 | AAGDIWVTR |