Skip to main content

Table 3 Baseline and IFN-induced expression of microRNAs and MxA-mRNA in patients with chronic hepatitis C according to the response to antiviral therapy (Peg-interferon (IFN) and ribavirin)

From: Differential expression of interferon-induced microRNAs in patients with chronic hepatitis C virus infection treated with pegylated interferon alpha

 

Baseline expression*

Fold IFN induction*

 

Responders

Non-responders

Responders

Non-responders

miR-1

2.61 ± 4.03

(0.52)

3.12 ± 6.84

(0.07)

5.26 ± 10.23

(1.29)

1.35 ± 0.60

(1.00)

miR-30

222.10 ± 446.32

(19.61)

302.42 ± 543.38

(31.52)

3.09 ± 2.97

(1.20)

2.99 ± 2.21

(2.12)

miR-128

31.25 ± 42.77

(0.04)

0.01 ± 0.01

(0.007)

1.48 ± 0.90

(1.15)

1.27 ± 0.57

(1.08)

miR-196

1.19 ± 1.78

(0.05)

0.05 ± 0.03

(0.04)

1.85 ± 1.46

(1.21)

1.51 ± 0.87

(1.12)

miR-296

0.77 ± 1.01

(0.31)

34.23 ± 68.12

(0.21)

2.96 ± 2.97

(1.56)

1.18 ± 0.29

(1.07)

MxA

9.96 ± 11.17

(7.16)

8.67 ± 11.09

(2.99)

9.68 ± 8.02

(6.86)

1.82 ± 1.49

(0.97)

  1. *Data are expressed as mean ± standard deviation (median).