PD-1 expression on peripheral CD8+ TEM/TEMRA subsets closely correlated with HCV viral load in chronic hepatitis C patients

Table 1 Demographic and laboratory characteristics of participants enrolled in the study

Characteristics	Healthy control	HCV-infected patients
	(n = 17, F/M = 10/7)	(n = 37, F/M = 21/16)
Age (years) (mean ± SD)	42.034 ± 14.321	47.105 ± 16.990
ALT ^b level(IU/mL) (mean ± SD)	n.a.^a	43.324 ± 26.601
AST ^c level(IU/mL) (mean ± SD)	n.a.	39.250 ± 18.181
Y - GT ^d (IU/mL) (mean ± SD)	n.a.	28.916 ± 25.282
ALP ^e level(IU/mL) (mean ± SD)	n.a.	78.321 ± 36.270
Albumin level(g/L) (mean ± SD)	n.a.	47.354 ± 6.966
Total protein level(g/L) (mean ± SD)	n.a.	75.461 ± 15.782
Ratio of albumin to globulin (mean ± SD)	n.a.	1.410 ± 0.864
Total bilirubin level(μmol/L) (mean ± SD)	n.a.	12.280 ± 3.761
Direct bilirubin level (μmol/L) (mean ± SD)	n.a.	5.214 ± 5.390
Hemoglobin(g/L) (mean ± SD)	n.a.	139.620 ± 14.551
HCV genotyping (1b/2a)	n.a.	16/21
HCV RNA(log ₁₀ IU/ml) (mean ± SD)	n.a.	5.747 ± 1.244

^a n.a., not available or not applicable; ^bALT, Alanine aminotransferase; ^c AST, Aspartate aminotransfearse; ^d γóGT, γó glutamyltransferase; ^eALP, Alkaline phosphatase.

ISSN: 1743-422X