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Table 1 Summary and comparison of NiV infection and glycoprotein targeting in polarized epithelial and endothelial cells.

From: Nipah virus infection and glycoprotein targeting in endothelial cells

 

Epithelial cells (Weise et al., 2010)

Endothelial cells (this study)

Foci formation in NiV-infected polarized cell monolayers

yes

yes

Glycoprotein distribution in NiV-infected polarized cells

  

   F protein

bipolar

bipolar

   G protein

bipolar

bipolar

Glycoprotein distribution in polarized cells upon single expression

  

   F protein

basolateral

bipolar

   G protein

basolateral

bipolar

Distribution of glycoproteins with mutations in potential cytoplasmic sorting signals

  

   FY525A

apical

apical

   FY542/543A

basolateral

apical

   GY28/29A

apical

bipolar

   GL41/42A

basolateral

bipolar