Table 1 Contraindications situations for pegylated interferon and ribavirin therapy
From: Hepatitis C Treatment: current and future perspectives
Contraindications levels | Situations |
|---|---|
No more contraindications | - Regular alanine aminotransferase |
| Â | - Methadone maintenance |
| Â | - Anemia/thrombocytopenia and neutropenia |
| Â | - Restricted seizure |
| Â | - Age more than 65 years |
| Â | - Excess use of alcohol |
Virtual contraindications | - Depression |
| Â | - Psychosis |
| Â | - Autoimmune disorder |
| Â | - Drug abuser |
| Â | - Renal failure (with dialysis) |
Tough although not general contraindications | -Alcohol use |
| Â | -Coronary artery disorder |
| Â | - Hepatic decompensation |
| Â | - Transplantation of solid organ (except liver) |
General contraindications | - Pregnancy |