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Table 1 Contraindications situations for pegylated interferon and ribavirin therapy

From: Hepatitis C Treatment: current and future perspectives

Contraindications levels Situations
No more contraindications - Regular alanine aminotransferase
  - Methadone maintenance
  - Anemia/thrombocytopenia and neutropenia
  - Restricted seizure
  - Age more than 65 years
  - Excess use of alcohol
Virtual contraindications - Depression
  - Psychosis
  - Autoimmune disorder
  - Drug abuser
  - Renal failure (with dialysis)
Tough although not general contraindications -Alcohol use
  -Coronary artery disorder
  - Hepatic decompensation
  - Transplantation of solid organ (except liver)
General contraindications - Pregnancy