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Table 5 Herpes viruses and clinical parameters in pediatric lymphoma patients

From: Presence of Human Herpes Virus 6 (HHV6) in pediatric lymphomas: impact on clinical course and association with cytomegalovirus infection

Factor

HHV6 n(%)

CMV n(%)

Both n(%)

Negative n(%)

p value

Fever n = 22

3(14)

3(14)

7(32)

9(40)

0.100

Rash n = 9

0(0)

1(11)

2(22)

6(67)

0.479

Organomegaly n = 13

2(15)

1(8)

2(15)

8(62)

0.526

Med. mass n = 18

2(11)

4(22)

2(11)

10(56)

0.869

Mucositis n = 10

2(20)

1(10)

7(70)

0(0)

< 0.001

Other infection n = 14

3(21)

0(0)

8(58)

3(21)

0.004

Duration of FN (n = 28)

     

Low Risk (< 10 d) n = 15

1(7)

3(20)

2(13)

9(60)

0.136

High Risk (≥ 10 d) n = 13

2(15)

0(0)

7(54)

4(31)

 

ANC (Median = 0.8)

     

Mild(≥ 0.8)n = 25

3(12)

6(24)

1(4)

15(60)

0.570

Severe (< 0.8)n = 25

3(12)

1(4)

9(36)

12(48)

 

Plt count

     

≥96 n = 25

4(16)

5(20)

2(8)

14(56)

1.000

< 96 n = 25

2(8)

2(8)

8(32)

13(52)

 

Hb

     

≥ 9.1 n = 25

3(12)

5(20)

1(4)

16(64)

0.256

< 9.1 n = 25

3(12)

2(8)

9(36)

11(44)

 

Mono

     

≥ 0.4 n = 25

3(12)

5(20)

2(8)

15(60)

0.570

< 0.4 n = 25

3(12)

2(8)

8(32)

12(48)

 

Lymph

     

≥ 0.5 n = 25

3(12)

4(16)

1(4)

17(68)

0.089

< 0.5 n = 25

3(12)

3(12)

9(36)

10(40)

 
  1. Med. Mass: Mediastinal mass, FN: Febrile neutropenia, ANC: absolute neutrophil count, Plt: Platelet count, Hb: hemoglobin concentration, Mono: monocyte, Lymph: Lymphocyte, HHV6: herpes virus 6 single infection, CMV: cytomegalovirus single infection, Both: positive for HHV6/CMV DNA, Negative: negative for herpes viruses
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Virology Journal

ISSN: 1743-422X