Table 4 HIV-1 co-receptor prediction based on genotypic algorithm and its sensitivity and specificity in ART population
Methods | prediction HIV-1 co-receptor usage | Consistency with phenotypic | ||
|---|---|---|---|---|
CCR5 (%) | CXCR4 (%) | sensitivity | specificity | |
11/25 rule | 28(65.1) | 15(34.8) | 54.6% | 90.0% |
WebPSSM | 29(67.4) | 14(32.6) | 50.0% | 90.0% |
geno2pheno | 15(34.8) | 28(65.1) | 68.2% | 40% |