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Table 3 Association of HIV-1 co-receptor usage with the net charge of V3 loop

From: Co-receptor usage and prediction of v3 genotyping algorithms in hiv-1 subtype b' from paid blood donors experienced anti-retroviral therapy in chinese central province

Characteristic Distributionband frequencycof net charge of V3 loop
Groups tropism Na Mean ± Std 2(%) 3(%) 4(%) 5(%) 6(%) 7(%)
Drug-naïve R5 66 3.91 ± 1.05 3(3.7) 22(27.2) 25(37.9) 12(18.2) 2(3.0) 2(3.0)
  X4/R5 15 4.53 ± 0.74 0   9(60.0) 4(26. 7) 2(13.3) 0
ART R5 20 3.75 ± 1.21 1(5.0) 7(35.0) 7(35.0) 3(15.0) 2(10.0) 0
  X4/R5 22 4.86 ± 1.25 1(4.6) 3(13.6) 5(22.7) 4(18.2) 7(31.8) 2(9.1)
  1. Note: a: the number of cases;
  2. b:it is the net charge of V3 loop according to the formula (V3 net charge=(R+K)-(D+E));
  3. c:it is the frequency of b in the a.
  4. bold: No. of net charge of V3 for R5-tropic viruses distributed mainly below 4, occupied more than 70%;
  5. bold and italic: No. of net charge of V3 for X4-tropic viruses distributed mainly above 4 in drug-naïve group, above 5 in ART group, occupied more than 60%