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Figure 3 | Virology Journal

Figure 3

From: Extra-cellular release and blood diffusion of BART viral micro-RNAs produced by EBV-infected nasopharyngeal carcinoma cells

Figure 3

Detection of the BART miRNAs secreted by NPC cells in association with exosomes. Presence of 5 BART miRNAs - miR-BART1-5p and 5 (cluster 1) and miR-BART 7-3p, 12 and 13 (cluster 2) - was assessed by real time PCR following multiplex RT. Each BART miRNA is relatively abundant in the exosomes from C15 NPC cells and to a lesser extent from NAD+C15 LCL cells. The same BART miRNAs are barely detectable in C17 exosomes. As expected the BART miRNAs are absent in exosomes from Hela cells which are EBV-negative. Their absence in the exosomes from Daudi cells is consistent with their absence in Daudi cellular RNA (see Figure 1). Note that the 2-ΔCT index for miR-BART 7-3p is several times higher than for other BART microRNAs. These data are representative of two similar experiments.

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Virology Journal

ISSN: 1743-422X