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Figure 4 | Virology Journal

Figure 4

From: Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication

Figure 4

Analysis of ISRE-luciferase promoter activation due to intracellular expression of IRF9-Stat fusion proteins. R15-3 cells were transfected with IRF9, IRF9-S1C or IRF9-S2C plasmid and cultured (-) and (+) IFN-α (1,000 IU/ml). At 48 hours FL and RL activity were measured. Values are expressed in RL normalized units and error bars represent the SEM from three experiments. The Student's t-test was used to compare IRF9 with and without IFN to IRF9-S1C, IRF9-S2C and IRF9-S1C plus IRF9-S2C with and without IFN. Values <.05 were considered significant.

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Virology Journal

ISSN: 1743-422X