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Figure 3 | Virology Journal

Figure 3

From: Interaction of mumps virus V protein variants with STAT1-STAT2 heterodimer: experimental and theoretical studies

Figure 3

Interaction model V-STAT1-STAT2. (A) Heterodimer model of STAT1-STAT2 by the SH2-domain (STAT1 PDB: 1YVL and 3D model of STAT2 from 1YVL and 1BF5). Heterodimer model shows the following residues: Tyr690 and Tyr701 (orange), nuclear localization signal residues (pink), lysine residues to ubiquitylation (Ub) (blue). (B) Interaction of STATs heterodimer with VWT by Trp-motif and STAT2. (C) Interaction of heterodimer with VGly by STAT2, lysine residues (Ub) (blue). In B and C, the boxes at right show the interaction site.

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Virology Journal

ISSN: 1743-422X