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Figure 3 | Virology Journal

Figure 3

From: Characterization of an H3N2 triple reassortant influenza virus with a mutation at the receptor binding domain (D190A) that occurred upon virus transmission from turkeys to pigs

Figure 3

Binding of parental TK04-190Asp and mutant TK04-190Ala viruses to plasma membrane preparations (PMP) from human, pig and turkey primary tracheal/bronchial epithelial cells. Both viruses bound with similar efficiency to PMP from HAEC and PEC but not TEC (P-value < 0.02) at high virus titer (64 HA). Nonetheless, 190Ala virus showed decreased binding efficiency (P-value <0.04 and <0.019 for HAEC and PEC respectively) to all PMP at lower titers.

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Virology Journal

ISSN: 1743-422X