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Table 2 HPV detection by HC-II assay and PCR Method in Clinico-pathogical parameter (OSMF grading according to Pindborg and T and N category according to UICC classification) in OSMF cases.

From: Comparative study between the Hybrid Capture II test and PCR based assay for the detection of human papillomavirus DNA in oral submucous fibrosis and oral squamous cell carcinoma

Clinico-pathogical Diagnosis

No (%) HPV detection by HC-II assay and PCR Method

 

PCR+ve,

HC-II+ve [n = 42]

PCR+ve,

HC II-ve [n = 12]

PCR-ve,

HC-II+ve [n = 15]

PCR-ve,

HC-II-ve [n = 139]

Potentially malignant oral lesions: Oral sub mucous fibrosis (OSMF), n = 208 cases

Grade-I (26)

5 (11.9%)

1 (8.33%)

2 (13.33%)

18 (12.94%)

Grade-II (43)

9 (21.42%)

3 (25.0%)

2 (13.33%)

29 (18.9%)

Grade-II (55)

11 (26.12%)

3 (25.0%)

4 (26.67%)

37 (22.61%)

Grade IV (84)

17 (40.47%)

5 (41.67%)

7 (46.6%)

55 (39.56%)