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Table 1 HPV detection by HC-II assay and PCR in OSMF and OSCC patients in the following categories.

From: Comparative study between the Hybrid Capture II test and PCR based assay for the detection of human papillomavirus DNA in oral submucous fibrosis and oral squamous cell carcinoma

Variables

OSMF cases (n = 208)

OSCC cases (n = 222)

 

PCR+ve, HC-II+ve (N = 42)

PCR+ve, HC II-ve (N = 12)

PCR-ve, HC-II+ve (N = 15)

PCR-ve, HC-II-ve (N = 139)

PCR+ve, HC-II+ve (N = 61)

PCR+ve, HC II-ve (N = 11)

PCR-ve, HC-II+ve (N = 09)

PCR-ve, HC-II-ve (N = 141)

Gender

        

Male

28 (66.6%)

07 (58.3%)

11 (73.3%)

77 (55.4%)

42 (68.8%)

07 (63.6%)

06 (66.7%)

91 (64.5%)

Female

14 (33.3%)

05 (41.7%)

04 (26.7%)

62 (44.6%)

19 (31.1%)

04 (36.4%)

03 (33.3%)

50 (35.5%)

Age (Years)

        

< 45

26 (61.9%)

04 (33.3%)

07 (46.7%)

68 (48.9%)

39 (63.9%)

05 (45.5%)

05 (55.5%)

40 (28.4%)

≥45

16 (38.1%)

08 (66.6%)

08 (53.3%)

71 (51.1%)

22 (36.1%)

06 (54.5%)

04 (44.4%)

101(71.6%)

Tobacco

        

Chewing Status

        

Chewers

38 (90.5%)

10 (83.3%)

12 (80.0%)

96 (69.1%)

52 (85.2%)

08 (72.7%)

07 (77.8%)

109(77.3%)

Non Chewer

04 (9.5%)

02 (16.6%)

03 (20.0%)

43 (30.9%)

09 (14.7%)

03 (27.3%)

02 (22.2%)

32 (22.7%)

Smoking Status

        

Smokers

35 (83.3%)

08 (66.6%)

09 (60.0%)

111(79.8%)

51 (83.6%)

07 (63.6%)

05 (55.5%)

121(85.8%)

Non smokers

07 (16.6%)

04 (33.3%)

06 (40.0%)

28 (20.1%)

10 (16.4%)

04 (36.4%)

04 (44.4%)

20 (14.2%)

Alcohol

        

Drinker

40 (95.2%)

08 (66.6%)

12 (80.0%)

105(75.5%)

40 (65.6%)

05 (45.4%)

07 (77.8%)

120 (85.1%)

Drinker

02 (4.7%)

04 (33.3%)

03 (20.0%)

34 (24.5%)

21 (34.4%)

06 (54.5%)

02 (22.2%)

 

Non Drinker

       

21 (14.9%)

Location

        

Oral Cavity

18 (42.8%)

05 (41.7%)

06 (40.0%)

68 (48.9%)

32 (52.5%)

05 (45.4%)

03 (33.3%)

72 (51.1%)

Tongue

12 (28.6%)

03 (25.0%)

04 (26.6%)

13 (9.4%)

12 (19.7%)

03 (27.3%)

04 (44.4%)

21 (14.9%)

Lip

09 (21.4%)

02 (16.6%)

04 (26.6%)

28 (20.1%)

08 (13.1%)

02 (18.2%)

02 (22.2%)

20 (14.2%)

Hard & soft palate

03 (7.1%)

02 (16.6%)

01 (6.7%)

30 (21.6%)

09 (14.7%)

01 (9.1%)

00 (0.0%)

28 (19.8%)

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Virology Journal

ISSN: 1743-422X