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Table 5 The differences in the main clinical features of children with multiple infections or a single infection.

From: Coinfection with EBV/CMV and other respiratory agents in children with suspected infectious mononucleosis

Clinical features

A(n = 31)

B(n = 14)

C(n = 29)

D(n = 54)

E(n = 12)

F(n = 22)

H. stay, days

10.87 ± 4.11**

10.07 ± 4.23

7.69 ± 3.24*

8.09 ± 3.15*

9.08 ± 3.23

7.73 ± 3.88*

D. of fever, days

7.39 ± 3.93**

5.79 ± 4.89

4.62 ± 4.07*

4.80 ± 4.44*

7.33 ± 5.63

4.32 ± 3.20*

Fever

30 (96.8%)**

11 (78.6%)*

22 (75.9%)*

43 (79.6%)*

11 (78.6%)*

19 (86.4%)*

Rash

7 (22.6%)

0 (0)

7 (24.1%)

9 (16.7%)

1 (8.33%)

5 (22.7%)

Lymphadenopathy

16 (51.6%)**

7 (50.0%)**

9 (31.0%)*

13 (24.1%)*

3 (25.0%)*

9 (40.9%)

Pharyngitis

31 (100%)

13 (92.9%)

28 (96.6%)

52 (96.3%)

11 (91.7%)

22 (100%)

Palatal petechiae

6 (19.4%)

4 (28.6%)

6 (20.7%)

8 (14.8%)

4 (33.3%)

4 (18.2%)

Hepatomegaly

7 (22.6%)*

3 (21.4%)*

3 (10.3%)**

4 (7.41%)**

0 (0)

2 (9.09%)**

Splenomegaly

3 (9.38%)

1 (7.41%)

1 (3.45%)

2 (3.70%)

0 (0)

1 (4.55%)

ALC > 10%

8/10 (80.0%)**

5/10 (50.0%)**

2/10 (20.0%)*

8/32 (25.0%)*

2/7 (28.6%)*

4/12 (33.3%)*

Elevated ESR

14/17 (82.4%)**

7/9 (77.8%)*

11/18 (61.1%)*

15/29 (51.7%)*

5/5 (100%)**

8/13 (61.5%)*

CRP > 10 mg/L

9/17 (52.9%)*

5/10 (50.0%)*

9/18 (50.0%)*

16/32 (50.0%)*

7/7 (100%)**

12/15 (80.0%)**

ALF

9/18 (50.0%)*

3/7 (42.3%)*

0/7 (0)

4/17 (23.5%)**

0/3 (0)

2/3 (66.7%)*

  1. A. EBV/CMV primary infection with multiple pathogens. B. EBV/CMV primary infection with a single or no other pathogen. C. EBV/CMV past infection with multiple pathogens. D. EBV/CMV past infection with a single or no other pathogen. E. EBV/CMV-uninfected children with multiple pathogens. F. EBV/CMV-uninfected children with a single or no other pathogen. Between * and **, the p value < 0.05. H. stay: hospital stay; D. of fever: duration of fever; ALC: atypical lymphocytes; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; ALF: abnormal liver function (alanine aminotransferase or aspartate aminotransferase higher than 46 U/L); WBC: white blood cell.