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Table 1 The main clinical features in patients grouped by EBV detection.

From: Coinfection with EBV/CMV and other respiratory agents in children with suspected infectious mononucleosis

Clinical features

primary infected

(n = 40)

past infected

(n = 48)

uninfected

(n = 76)

Age

8-164 months

2-163 months

1-140 months

   1-12 months

3 (7.50%)

7 (14.6%)

20 (26.3%)

   12-36 months

17 (42.5%)

11 (22.9%)

23 (30.3%)

   36-72 months

8 (20.0%)

17 (35.4%)

21 (27.6%)

   > 72 months

12(30.0%)

13(27.1%)

12(15.8%)

Sex, male/female

20/20

20/18

52/24

Length of stay, days

9.53 ± 3.52*

7.71 ± 3.07**

9.11 ± 4.11*

Duration of fever, days

6.43 ± 4.21

6.04 ± 4.19

4.99 ± 4.67

Fever

36 (90%)

42 (87.5%)

64 (84.2%)

Rash

8 (20.0%)

9 (18.8%)

13 (17.1%)

Lymphadenopathy

24 (60.0%)*

14 (29.2%)**

29 (38.2%)**

Pharyngitis

39 (97.5%)

45 (93.8%)

75 (98.7%)

Palatal petechiae

9 (22.5%)

13 (27.1%)

16 (21.1%)

Hepatomegaly

8 (20.0%)*

9 (18.8%)*

7 (9.21%)**

Splenomegaly

4 (10.0%)

3 (6.25%)

4 (5.26%)

ALC < 10%

10/27 (37.0%)*

11/26 (42.3%)**

11/46 (23.9%)*

Elevated ESR

16/28 (57.1%)

18/31 (58.1%)

19/43 (44.2%)

CRP > 10 mg/L

13/26 (50.0%)*

22/33 (66.7%)**

31/48 (64.6%)**

ALF

7/22 (31.8%)

5/18 (27.8%)

10/24 (41.7%)

WBC count, 109/L

11.94 ± 8.58

10.20 ± 5.67

10.47 ± 5.99

Neutrophils, %

40.48 ± 24.43

49.07 ± 21.81

41.99 ± 26.24

Lymphocytes, %

48.37 ± 23.65

39.86 ± 22.03

45.65 ± 25.58

Monocytes, %

9.98 ± 6.12

9.58 ± 4.61

9.86 ± 6.26

Platelets, 109/L

263.61 ± 125.37

286.38 ± 142.72

288.90 ± 130.82

Hemoglobin, g/L

116.53 ± 8.85

117.68 ± 10.83

117.90 ± 10.23

  1. Between * and **, the p value < 0.05. ALC: atypical lymphocytes; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; ALF: abnormal liver function (alanine aminotransferase or aspartate aminotransferase higher than 46 U/L); WBC: white blood cell.