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Figure 5 | Virology Journal

Figure 5

From: Inactivation of respiratory syncytial virus by zinc finger reactive compounds

Figure 5

Immunogenicity of AT-2-inactivated RSV in the cotton rat model. Cotton rats were immunized intramuscularly with AT-2-inactivated RSV ("RSV/AT-2"), AT-2-inactivated RSV adjuvanted with Ribi emulsion (adjRSV/AT-2) or formalin-inactivated RSV (FI-RSV). Control animals remained unvaccinated ("control") or were immunized via repeated infection with live RSV ("live RSV"). All animals were challenged with RSV and sacrificed 4 days after infection for analysis of pulmonary viral load (A) and histopathology (B). Results are the mean ± SEM for 4 animals per group. *p < 0.05 when compared to the "control" group.

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