Figure 2
From: Inactivation of respiratory syncytial virus by zinc finger reactive compounds
Inability of respiratory syncytial virus inactivated with AT-2 to replicate in the lungs of cotton rats. RSV was inactivated by incubation with 10 mM AT-2 for 24 hrs at 37°C. Virus was then diluted with PBS and used to intranasally infect cotton rats. Control animals received sham-treated RSV. Four days post-challenge animals were sacrificed and lungs were collected for viral titrations. Results shown are the mean log (viral titer) ± SE for 4 animals per group.