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Figure 4 | Virology Journal

Figure 4

From: Peptides derived from the HIV-1 integrase promote HIV-1 infection and multi-integration of viral cDNA in LEDGF/p75-knockdown cells

Figure 4

INr peptides stimulate viral cDNA integration in LEDGF/p75-knockdown cells. HeLa P4 (□) and HeLaP4/shp75Cl15 (LEDGF/p75-knockdown) (■) cells were incubated with or without 100 μM INS or INr and infected with wt HIV-1 at a MOI of 1.0. AZT was used at 2 μM concentration. The average number of integration events per cell was estimated as described in Methods.

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