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Table 1 In vitro neutralization assays of monoclonal antibodies*

From: Monoclonal antibody induced with inactived EV71-Hn2 virus protects mice against lethal EV71-Hn2 virus infection

Antibodies

Neutralization titers

Convalscent patient serum

1:64

4D10

1:8

3B11

1:16

4E8

1:64

4C6

1:64

4G9

<1:4

1A5

<1:4

2F7

<1:4

Normal mouse serum

<1:4

  1. *50 μl of virus suspension containing 100TCID50 EV71 Hn2 was pre-incubated with 50 μl of serial two-fold dilutions of antibodies for 30 min before adding to Vero cells in 96-well plates. After 3 days at 37°C, the titer of neutralizing antibody was read as the highest dilution that gave complete protection from CPE.
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Virology Journal

ISSN: 1743-422X