Figure 5From: Effective inhibition of HCMV UL49 gene expression and viral replication by oligonucleotide external guide sequences and RNase PInhibition directed by DNA-based EGS is dose-dependent. Quantitative RT-PCR showed that when the concentration of EGS324 was 2.5 nM, the inhibition efficiency was 15%, and then 5 nM was 22%, 10 nM was 31%, 20 nM was 43%, 40 nM was 51%, 80 nM was 75%, and 160 nM was 75.6%. Mock group was treated with a 50 bp random DNA fragment.Back to article page