Figure 1
From: Inhibition of lentivirus replication by aqueous extracts of Prunella vulgaris
Water extracts of P. vulgaris inhibit lentiviral infectivity with low cell toxicity. DMSO, water extracts and ethanol extracts of P. vulgaris were diluted in media to 0.2% (water extracts: 66 μg/mL of Ames 27664, 42.2 μg/mL of Ames 27665, 59.6 μg/mL of Ames 27666, or 62.4 μg/mL of Ames 27748 and ethanol extracts: 66.8 μg/mL of Ames 27664, 69.2 μg/mL of Ames 27665, 64.2 μg/mL of Ames 27666, or 67.4 μg/mL of Ames 27748). Equivalent quantities of EIAVWSU5 were added to each well of ED cells along with the diluted extracts. Forty h following infection, cells were fixed and immunostained for viral antigen. Cell-viability studies were performed in parallel. Cell viability and virus infectivity are shown as a ratio of the values in the presence of the extracts divided by the DMSO control. Shown are the averages and standard errors of three experiments performed in triplicate. *, p < 0.05; **, p < 0.001.