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Table 1 Comparison of relative infectivity and enhancements for different EGP mutants

From: Expression of Ebolavirus glycoprotein on the target cells enhances viral entry

Mutant Relative Infectivity in 293T Cells (%) Relative Enhancement in Wt EGP Tet-On cells(%)
Wt 100 290
L57I 9.50 221
K95A 4.00 133
I170A 26.10 213
G528A 74.42 238
F535R 0.02 71
G536A 0.07 109
P537A 3.37 230
L558A 6.92 324
L561A 0.02 73
R580A 7.80 824
R596A 0.02 108
I623A 0.02 96
D629A 0.74 1188
F630A 0.68 789
  1. *Mutant completely defective in mediating viral entry are shown in bold font