Table 1 Comparison of relative infectivity and enhancements for different EGP mutants
From: Expression of Ebolavirus glycoprotein on the target cells enhances viral entry
Mutant | Relative Infectivity in 293T Cells (%) | Relative Enhancement in Wt EGP Tet-On cells(%) |
|---|---|---|
Wt | 100 | 290 |
L57I | 9.50 | 221 |
K95A | 4.00 | 133 |
I170A | 26.10 | 213 |
G528A | 74.42 | 238 |
F535R | 0.02 | 71 |
G536A | 0.07 | 109 |
P537A | 3.37 | 230 |
L558A | 6.92 | 324 |
L561A | 0.02 | 73 |
R580A | 7.80 | 824 |
R596A | 0.02 | 108 |
I623A | 0.02 | 96 |
D629A | 0.74 | 1188 |
F630A | 0.68 | 789 |