Table 3 Sequence, positions, and tropism of each of the 14 ribozymes used in this study
hRz # | Sequence of target RNA (5'→3') | Target triplet and position in genome | DENV-2 strains targeted |
|---|---|---|---|
1 | AGGAAAAGUC GUGCAAC | GUC 1325 (ENV) | NGC |
2 | GUUUUAGGUC GCCUGAU | GUC 1988 (ENV) | NGC |
3 | UAGCCCAGUC AACAUAG | GUC 2035 (ENV) | NGC |
4 | CAUAGGAGUC AUUAUCA | GUC 2323 (ENV) | NGC |
5 | UCACUGUC UGUGUC | GUC 2367 (ENV) | All strains |
6 | AUAGUGUC AUCAGUGAA | GUC 8272 (NS5) | All strains |
7 | AAAGAAGUC AGGCCA | GUC 10420 (3'NCR) | All strains |
8 | GCAUGGUA CCUGUGG | GUA 4503 (NS2B) | All strains |
9 | GACUCAAAACUC AUGUCAGC | CUC 2974 (NS1) | All strains |
10 | AUGGAAAUC AGACCATT | AUC 3430 (NS1) | All strains |
11 | GGAAGCUGUA CGCAUGG | GUA 10528 (3'NCR) | All strains |
12 | UGAAGCUGUA GUCUC | GUA 10624 (3'NCR) | All strains |
13 | AUGCCAUC CAUGAA | AUC 10244 (NS5) | All strains |
14 | CUGUUGAAUC AACAGGU | AUC 10768 (3'NCR) | All strains |