Figure 3

Stimulation of the Mx promoter by the different IFN-α subtypes. Huh7 cells were transfected with a plasmid containing the luciferase reporter gene under the control of the human Mx promoter. After stimulation by IFN-α2a, 17, 8, 7 and 1, luciferase was quantified. The results correspond to the ratio between the value obtained with IFN-α and the value obtained in the absence of interferon and were the mean of two independent experiments in triplicate. An asterisk indicates the values that were significantly different from those for IFN-α2a at the same concentration.