Figure 2

Determination of the IC50% for three IFN-α subtypes. Huh7-infected cells were cultured with or without different concentrations (in pg/mL) of IFN-α2a (open circles), IFN-α17 (closed squares) and IFN-α1 (open triangle). The virus yield was determined using the FFU method. The results represent the mean of four independent experiments. The p values were < 0.05 at all concentrations for the IFN-α2a vs. IFN-α17 comparison (*) and at 12.5 and 25 pg/mL for the IFN-α2a vs. IFN-α1 comparison (+).