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Table 2 Anti-HBs levels in vaccinated newborns with different anti-preS1 peptide (21–32, 32–47, 94–117) reactivities at time T9

From: PreS1 epitope recognition in newborns after vaccination with the third-generation Sci-B-Vac™ vaccine and their relation to the antibody response to hepatitis B surface antigen

Reactivity with

Number

Anti-HBs (IU/L)

Probability*

3 preS1 peptides

n = 7

23 688 ± 6 183 a/

 

2 preS1 peptides

n = 4

22 890 ± 10 670 b/

ns

1 preS1 peptide

n = 12

11 919 ± 8 669 c/

p < 0.025

0 preS1 peptide

n = 5

2 065 ± 1 105 d/

p < 0.05

  1. *the a/ compared with the b/, c/ or d/ groups of vaccinated newborns (Mann-Whitney test)
  2. ns = not significant
  3. T9 = three months after the third injection
  4. Anti-HBs (mean ± SEM)