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Table 1 p24gag Concentration (pg/ml) in Supernatantsa of Cotton Rat Cells infected with Different HIV-1 Isolates.

From: Expression of Human CD4 and chemokine receptors in cotton rat cells confers permissiveness for productive HIV infection

Cell Clonesb

 

Virus Isolatesc

 

Mock

BAL

MN

US1

CCRT

<15

331 ± 20

110 ± 14

54 ± 2

CCRT K4

<15

33 ± 6

25095 ± 3191

n.d.d

CCRT C6

<15

18477 ± 1119

35 ± 2

16635 ± 1743

VCRT

<15

142 ± 12

89 ± 9.5

46 ± 2

VCRT C17

<15

1072 ± 37

106 ± 8

40 ± 3

  1. aSupernatants of each infection experiments were tested for the presence of p24gag in duplicates at several time post infection (day 1 to 24) and the peak concentration is presented. Results represent means ± SD of at lease two experiments.
  2. bCotton rat cell clones expressing human CD4 with CXCR4 (CCRT K4), or with CCR5 (CCRT C6 and VCRT C17).
  3. cHIV-1 viral isolates X4-tropic (MN) and R5-tropic (BAL and US1).
  4. d not determined.
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Virology Journal

ISSN: 1743-422X