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Figure 7 | Virology Journal

Figure 7

From: In vitro host range, multiplication and virion forms of recombinant viruses obtained from co-infection in vitro with a vaccinia-vectored influenza vaccine and a naturally occurring cowpox virus isolate

Figure 7

Cellular and viral localization of the influenza virus haemagglutinin protein. Vero cells were infected with MVA-HANP and HA + hybrid progenies and processed for immunoelectron microscopy as detailed in methods. Rec 1 infected Vero cells (A, B) and Rec 2 infected Vero cells (C-F). (A): arrow (plasma membrane), arrow heads (IMVs); (B): arrow (plasma membrane), arrow heads (CEVs); (C): arrow (plasma membrane), large arrow head (trans-Golgi membrane), small arrow heads (immature viruses); (D): arrow (plasma membrane), large arrow heads (Golgi apparatus), small arrow (cell associated vesicle); (E): arrow (plasma membrane), arrow heads (CEVs); (F): arrow (plasma membrane), large arrow heads (EEVs), small arrow head (plasma membrane projection). The same results were obtained with MVA-HANP and Rec 3 (data not shown). IMV, intracellular mature virus; CEV, cell associated enveloped virus; EEV, extracellular enveloped virus. Bars, 100 nm (A-F).

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Virology Journal

ISSN: 1743-422X