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Table 3 Evidence for infection in Grave's disease

From: Viruses and thyroiditis: an update

in favour of infection

references

not in favour of infection

references

Levels of data: Epidemiological

seasonality of month of birth

[44]

  

higher diagnosis and relapse rate in spring and summer

[41, 42]

  

geographical distribution

[43]

  

antibodies or disease onset following subacute thyroiditis

[47–50]

nonspecific response to the inflammatory rection ?

[32]

HTLV1

[62]

  

HIV

[65]

lack of anti-thyroid antibodies before the beginning of HAART

[75]

Serological and/or circulating viral genome

HTLV1

[57, 60–62]

  

HIAP-1

[78]

  

HFV

[81, 84]

HFV

[20, 82, 83]

parvovirus

[106]

Enterovirus

[121]

HHV6, HHV7

[101]

  

Direct evidence of infection

HTLV-1

[64]

  

HIV-1

[70]

SV40

[72, 73]

  

HIAP-1

[79]

HFV

[19, 80]

HFV

[83]

SV40

[85]

HSV, CMV

[97]