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Figure 5 | Virology Journal

Figure 5

From: Incorporation of membrane-bound, mammalian-derived immunomodulatory proteins into influenza whole virus vaccines boosts immunogenicity and protection against lethal challenge

Figure 5

Proliferation induced by CYT-IVACs is specific and dependent on the respective membrane-bound cytokine. Proliferation of cytokine responsive cell lines CTLL-2 (A) and CT.4s (B) was measured following incubation with β-propiolactone inactivated mIL-2 or mIL-4 bearing CYT-IVACs. IL-2 CYT-IVAC induced proliferation of CTLL-2 cells was inhibited in a dose dependent manner with anti-mIL-2 neutralizing antibodies (C). Recombinant protein was used as a positive control.

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Virology Journal

ISSN: 1743-422X