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Figure 4 | Virology Journal

Figure 4

From: Incorporation of membrane-bound, mammalian-derived immunomodulatory proteins into influenza whole virus vaccines boosts immunogenicity and protection against lethal challenge

Figure 4

Membrane-bound immunomodulators retain bioactivity following viral inactivation. Cytokine specific indicator cell lines (bone marrow cells, BM; CTTL-2; or CT.4s) were incubated with decreasing concentrations of β-propiolactone inactivated wild-type vaccine or GM-CSF CYT-IVAC (A), IL-2 CYT-IVAC (B) or IL-4 CYT-IVAC (C). Proliferation was determined by Alamar Blue® reduction. Recombinant protein was used as the positive control.

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Virology Journal

ISSN: 1743-422X