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Table 1 Comparison of genetic stability of different replication-competent SFV4-based vectors in BHK-21 cells

From: Properties and use of novel replication-competent vectors based on Semliki Forest virus

 

P1

P2

P3

P4

P5

SFV4-T37/17-d1EGFP

100%

100%

100%

80%

70%

SFV4-T26/20-d1EGFP

100%

96%

85%

59%

41%

SFV4-T99/45-d1EGFP

96%

75%

65%

41%

15%

SFV4-d1EGFP-M26

100%

50%

11%

0%

0%

SFV4-d1EGFP-M37

96%

64%

38%

3%

0%

SFV4-d1EGFP-M96

96%

50%

19%

11%

0%

  1. The d1EGFP expression was transient and relatively weak. Therefore, it is possible that some d1EGFP positive plaques were counted as d1EGFP negative and the stability of constructs was somewhat under-estimated.