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Figure 5 | Virology Journal

Figure 5

From: Engineering the vaccinia virus L1 protein for increased neutralizing antibody response after DNA immunization

Figure 5

Effects of signal peptide and presence or absence of transmembrane domain on VACV neutralizing antibodies. Mice (n = 5) were immunized at 0 time and weeks 2, 4 and 6 with plasmids using a gene gun. Mice were bled at 2 weeks after each of the first three immunizations and 3 weeks after the last. Neutralizing activity was determined by flow cytometry. Arrows point to days of immunization

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