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Figure 5 | Virology Journal

Figure 5

From: Mutagenesis of the transmembrane domain of the SARS coronavirus spike glycoprotein: refinement of the requirements for SARS coronavirus cell entry

Figure 5

Pore formation, as shown by the transfer of calcein. Cells expressing ACE-2 (calcein loaded, green) and (mutant) S (CMAC loaded, blue) were mixed and transfer of calcein from the ACE-2 expressing cells to the S-expressing cells was monitored. Double staining indicated calcein transfer and thus the existence of fusion pores.

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