Table 1 drug resistant mutation sites of primary variants and variants after culture 4 weeks
| Â | Â | first variants | fourth variants | ||
|---|---|---|---|---|---|
Virus variants | tropism | NRTIs | NNRTIs | NRTIs | NNRTIs |
V1 | R5X4 | - | K103N | - | - |
V2 | R5 | - | K101*EKQ, Y181C, G190A | - | G190A |
V3 | R5X4 | T215Y | K103N, Y181C | T215Y | K103N, Y181C |
V4 | R5X4 | D67N, K70R, T215F, K219Q | K103N, Y181C | D67N, K70R, T215F, K219Q | K103N, Y181C |
V5 | R5X4 | L74V | Y181C | V75T | V108I, Y181C |
V6 | R5X4 | - | K103N, Y181C | - | K103N, Y181C |
V7 | R5X4 | M41L, L74V, T215F | K101E, Y181C, G190S | M41L, L74V, T215F | K101E, Y181C, G190S |
V8 | R5 | K65R | K103N, Y181C | K65R | K103N, Y181C |
V9 | R5 | T69APST | V108FILV | - | - |
V10 | R5 | M41LM, T215Y | K103N, G190A | T215Y | K103N, G190A |
V11 | R5X4 | A62V, K70KN, V75T | Y188L | K70N, V75T | Y188L |
V12 | R5X4 | - | G190EV | - | G190A |
V13 | R5 | - | - | - | Y181C |