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Table 6 Expression of various lipase genes and genes involved with lipase activity in LCMV-WE infected macaque liver.

From: Gene expression in primate liver during viral hemorrhagic fever

    Pre-viremic Viremic
GenBank Accession no Symbol Gene description Fold changea p b Fold changea p b
NM_000483 APOC2 Apolipoprotein C-II 5.50 0.0003 3.53 0.0019
AK023348 GRN Granulin 1.84 0.0448 3.20 0.0007
NM_006854 KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 7.46 0.0056 7.36 0.0038
NM_000235 LIPA Lipase A, lysosomal acid, cholesterol esterase 2.17 0.1350 4.08 0.0059
NM_006033 LIPG Lipase, endothelial 2.20 0.4480 2.55 0.2950
AF077198 LYPLA1 Lysophospholipase I 7.16 0.0006 3.81 0.0008
BC006230 MGLL Monoglyceride lipase 3.27 0.0090 2.73 0.0162
D83485 PDIA3 Protein disulfide isomerase family A, member 3 6.36 0.0028 7.46 0.0010
AL542253 PLA1A Phospholipase A1 member A 1.37 0.0035 3.01 0.0124
NM_000300 PLA2G2A Phospholipase A2, group IIA (platelets) 2.19 0.7700 26.17 0.0218
AF145020 PLAA Phospholipase A2-activating protein 3.51 0.0026 2.69 0.0077
NM_002937 RNASE4 Ribonuclease, RNase A family, 4 45.25 0.00008 25.81 0.0001
  1. a Mean fold changes were calculated using a division of raw expression values between experimental sample and uninfected control.
  2. b All samples were analyzed separately. Changes in gene expression with a cutoff of 2.0-fold increased or decreased expression was used and, the p-value was calculated by Student's t-test. Data are displayed only where the, p ≤ 0.05. This p-value was used as a measure of the magnitude of the difference between groups and to determine significance of the modulation. The modulated genes in the pathway are listed in alphabetic order.